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MANNITOL (mannitol injection, USP) Description


Mannitol Injection, USP is a sterile, nonpyrogenic solution of mannitol in water for injection available in a fliptop vial for intravenous administration as an osmotic diuretic.

The content and characteristics are as follows:

Conc. (%) g/100 mL mOsmol/liter (calc.) pH*
May contain sodium bicarbonate and/or hydrochloric acid for pH adjustment.
25 25 1372 5.9 (4.5 to 7.0)

The solution contains no bacteriostat, antimicrobial agent, or added buffer (except for pH adjustment) and is intended only as a single-dose injection.

Mannitol, USP is chemically designated D-mannitol (C6H14O6), a white crystalline powder or free-flowing granules freely soluble in water. It has the following structural formula:

Chemical Structure

Water for Injection, USP is chemically designated H2O.

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